| Souleymane Ndiaye | New England Revolution | GK | 57 | 8 | 268 |
| Amadou Camara | Charlotte FC | DF | 54 | 15 | 228 |
| Souleymane Ondoua | Philadelphia Union | FW | 52 | 7 | 247 |
| Charles Diallo | Charlotte FC | MF | 37 | 11 | 184 |
| Boubacar Ba | Colorado Rapids | FW | 36 | 4 | 154 |
| Dele Ndidi | Colorado Rapids | DF | 31 | 17 | 207 |
| Moses Onuoha | New York Red Bulls | DF | 30 | 5 | 210 |
| Eric Malong | San Diego FC | DF | 29 | 10 | 187 |
| Felix Onuoha | Minnesota United FC | MF | 28 | 0 | 117 |
| Paul Ndiaye | LA Galaxy | MF | 28 | 5 | 119 |
| Moses Adjei | FC Cincinnati | GK | 25 | 1 | 150 |
| Omar Fall | Real Salt Lake | DF | 25 | 1 | 116 |
| Ayo Onuoha | Austin FC | DF | 24 | 11 | 124 |
| Tunde Kone | Columbus Crew | DF | 22 | 13 | 160 |
| Samuel Iheanacho | D.C. United | DF | 21 | 8 | 108 |
| Patrick Agyemang | Seattle Sounders FC | FW | 21 | 20 | 246 |
| Daniel Onyeka | New York City FC | MF | 20 | 13 | 152 |
| Kojo Ba | St. Louis City SC | FW | 20 | 3 | 99 |
| Paul Ekambi | Portland Timbers | MF | 20 | 13 | 160 |
| Kojo Ba | Houston Dynamo FC | FW | 19 | 2 | 103 |
| Felix Mbeumo | FC Cincinnati | DF | 19 | 2 | 122 |
| Emmanuel Onyeka | New England Revolution | DF | 16 | 15 | 162 |
| Emmanuel Adjei | Atlanta United FC | DF | 16 | 0 | 80 |
| Modou Camara | D.C. United | DF | 16 | 4 | 105 |
| Joseph Aboubakar | San Diego FC | FW | 16 | 4 | 152 |
| Dele Mbeumo | San Diego FC | DF | 15 | 1 | 111 |
| Tunde Ondoua | Nashville SC | MF | 14 | 3 | 148 |
| Felix Aboubakar | Houston Dynamo FC | GK | 14 | 0 | 147 |
| Patrick Kone | Vancouver Whitecaps FC | MF | 13 | 1 | 105 |
| Modou Opoku | Los Angeles Football Club | DF | 13 | 1 | 64 |
| David Traore | Seattle Sounders FC | DF | 12 | 8 | 90 |
| Bakary Amoah | Los Angeles Football Club | DF | 12 | 8 | 80 |
| Patrick Iheanacho | Philadelphia Union | FW | 11 | 1 | 65 |
| Kojo Agyemang | Colorado Rapids | FW | 11 | 8 | 96 |
| Chinonso Boateng | Chicago Fire FC | MF | 11 | 3 | 64 |
| Ibrahim Ekambi | Minnesota United FC | GK | 11 | 3 | 69 |
| Ayo Osayi | San Diego FC | FW | 10 | 1 | 95 |
| Solomon Asante | Vancouver Whitecaps FC | DF | 10 | 5 | 70 |
| Francis Malong | Columbus Crew | MF | 8 | 2 | 54 |
| Stephen Adjei | Sporting Kansas City | DF | 8 | 10 | 149 |
| Stephen Adjei | Chicago Fire FC | FW | 7 | 3 | 64 |
| Patrick Ndidi | Charlotte FC | DF | 7 | 1 | 29 |
| Obinna Anguissa | Orlando City SC | DF | 7 | 1 | 80 |
| Boubacar Appiah | San Jose Earthquakes | MF | 6 | 0 | 58 |
| Modou Ntcham | Toronto FC | DF | 6 | 3 | 84 |
| Kojo Owusu | Atlanta United FC | DF | 5 | 1 | 52 |
| David Moukoudi | New England Revolution | MF | 5 | 0 | 62 |
| Seyi Diallo | Seattle Sounders FC | FW | 5 | 4 | 60 |
| Adama Onuoha | Portland Timbers | MF | 5 | 2 | 80 |
| Ibrahim Iheanacho | San Diego FC | FW | 4 | 6 | 62 |
| Tunde Agyemang | Houston Dynamo FC | FW | 4 | 2 | 58 |
| Moussa Opoku | Sporting Kansas City | MF | 4 | 3 | 40 |
| Peter Iheanacho | Colorado Rapids | GK | 4 | 0 | 24 |
| Mamadou Bassey | Houston Dynamo FC | DF | 4 | 1 | 52 |
| Emmanuel Agyemang | Minnesota United FC | DF | 4 | 2 | 27 |
| Paul Ondoua | Philadelphia Union | DF | 3 | 0 | 29 |
| Benjamin Frimpong | FC Dallas | MF | 3 | 3 | 30 |
| Chidi Appiah | Vancouver Whitecaps FC | GK | 3 | 4 | 41 |
| Bakary Opoku | Houston Dynamo FC | FW | 3 | 4 | 45 |
| Peter Sow | New York City FC | MF | 2 | 3 | 43 |
| Ayo Moukoudi | New York City FC | DF | 2 | 0 | 34 |
| Charles Ondoua | Minnesota United FC | GK | 2 | 1 | 16 |
| Samuel Ndidi | Vancouver Whitecaps FC | DF | 2 | 6 | 85 |
| William Iheanacho | Atlanta United FC | DF | 1 | 12 | 227 |
| Kwame Ndidi | Orlando City SC | MF | 1 | 0 | 58 |
| Peter Adjei | Colorado Rapids | FW | 0 | 0 | 0 |
| Ibrahim Kone | Real Salt Lake | MF | 0 | 1 | 0 |
| Amadou Diallo | St. Louis City SC | DF | 0 | 4 | 98 |
| William Choupo | Colorado Rapids | MF | 0 | 0 | 41 |
| Chidi Appiah | Vancouver Whitecaps FC | MF | 0 | 7 | 85 |
| Paul Adjei | Vancouver Whitecaps FC | MF | 0 | 8 | 102 |
| Emmanuel Malong | Portland Timbers | DF | 0 | 7 | 127 |