| 1 | Chris Wondolowski |  San Jose Earthquakes | United States | 17 | 171 |
| 2 | Landon Donovan |  LA Galaxy | United States | 14 | 144 |
| 3 | Jaime Moreno |  D.C. United | Bolivia | 14 | 133 |
| 4 | Bradley Wright-Phillips |  New York Red Bulls | England | 8 | 108 |
| 5 | Robbie Keane | LA Galaxy | Ireland | 6 | 104 |
| 6 | Taylor Twellman |  New England Revolution | United States | 8 | 101 |
| 7 | Carlos Ruiz | LA Galaxy | Guatemala | 8 | 91 |
| 8 | Josef Martinez |  Atlanta United FC | Venezuela | 5 | 90 |
| 9 | Karol Swiderski |  Charlotte FC | Poland | 8 | 88 |
| 10 | Kenny Cooper |  FC Dallas | United States | 3 | 87 |
| 11 | Diego Valeri |  Portland Timbers | Argentina | 10 | 86 |
| 12 | Jozy Altidore |  Toronto FC | United States | 12 | 86 |
| 13 | Conor Casey |  Colorado Rapids | United States | 11 | 85 |
| 14 | Teemu Pukki |  Minnesota United FC | Finland | 8 | 85 |
| 15 | Sebastian Giovinco | Toronto FC | Italy | 5 | 83 |
| 16 | Jacob Shaffelburg |  Nashville SC | Canada | 8 | 83 |
| 17 | Dwayne De Rosario | D.C. United | Canada | 13 | 82 |
| 18 | Nery Castillo |  Chicago Fire FC | Mexico | 7 | 81 |
| 19 | David Villa |  New York City FC | Spain | 4 | 80 |
| 20 | Jack Harrison | New York City FC | England | 8 | 80 |
| 21 | Brenner |  FC Cincinnati | Brazil | 11 | 80 |
| 22 | Clint Dempsey |  Seattle Sounders FC | United States | 7 | 77 |
| 23 | Diego Rossi | Los Angeles Football Club | Uruguay | 10 | 76 |
| 24 | Joao Klauss |  St. Louis City SC | Brazil | 5 | 75 |
| 25 | Carlos Vela | Los Angeles Football Club | Mexico | 6 | 72 |
| 26 | Eric Wynalda | San Jose Earthquakes | United States | 8 | 71 |
| 27 | Steve Zakuani | Seattle Sounders FC | DR Congo | 10 | 71 |
| 28 | Josh Wolff | D.C. United | United States | 11 | 69 |
| 29 | Alvaro Saborio |  Real Salt Lake | Costa Rica | 10 | 69 |
| 30 | Ethan Finlay | Minnesota United FC | United States | 4 | 68 |
| 31 | Sven Becker |  Orlando City SC | Spain | 9 | 68 |
| 32 | Ercan Kara | Orlando City SC | Austria | 13 | 67 |
| 33 | Jason Kreis | Real Salt Lake | United States | 3 | 64 |
| 34 | Marcus Ingvartsen |  San Diego FC | Denmark | 3 | 63 |
| 35 | Samuel Diop | FC Cincinnati | Cameroon | 10 | 63 |
| 36 | Juan Pablo Angel | New York Red Bulls | Colombia | 4 | 62 |
| 37 | Chidi Ba | New York Red Bulls | Nigeria | 10 | 62 |
| 38 | Luciano Diaz | Nashville SC | Cuba | 9 | 61 |
| 39 | Daichi Hayashi |  Philadelphia Union | Japan | 8 | 61 |
| 40 | Ignacio Piatti | CF Montréal | Argentina | 6 | 60 |
| 41 | Preki |  Sporting Kansas City | United States | 9 | 60 |
| 42 | Fredy Montero | Seattle Sounders FC | Colombia | 7 | 60 |
| 43 | John Harkes | D.C. United | United States | 4 | 60 |
| 44 | George Weber | D.C. United | Bosnia | 10 | 60 |
| 45 | Niklas Weber | Los Angeles Football Club | Poland | 8 | 59 |
| 46 | Thiago Suarez | St. Louis City SC | Cuba | 8 | 59 |
| 47 | Hugo King | Nashville SC | Portugal | 8 | 59 |
| 48 | Taty Castellanos | New York City FC | Argentina | 4 | 58 |
| 49 | Jordan Morris | Seattle Sounders FC | United States | 9 | 58 |
| 50 | Roy Lassiter | D.C. United | United States | 2 | 58 |