| 1 | Chris Wondolowski |  San Jose Earthquakes | United States | 17 | 171 |
| 2 | Landon Donovan |  LA Galaxy | United States | 14 | 144 |
| 3 | Taylor Twellman |  New England Revolution | United States | 8 | 101 |
| 4 | Kenny Cooper |  FC Dallas | United States | 3 | 87 |
| 5 | Jozy Altidore |  Toronto FC | United States | 12 | 86 |
| 6 | Conor Casey |  Colorado Rapids | United States | 11 | 85 |
| 7 | Clint Dempsey |  Seattle Sounders FC | United States | 7 | 77 |
| 8 | Eric Wynalda | San Jose Earthquakes | United States | 8 | 71 |
| 9 | Josh Wolff |  D.C. United | United States | 11 | 69 |
| 10 | Ethan Finlay |  Minnesota United FC | United States | 4 | 68 |
| 11 | Jason Kreis |  Real Salt Lake | United States | 3 | 64 |
| 12 | Preki |  Sporting Kansas City | United States | 9 | 60 |
| 13 | John Harkes | D.C. United | United States | 4 | 60 |
| 14 | Jordan Morris | Seattle Sounders FC | United States | 9 | 58 |
| 15 | Roy Lassiter | D.C. United | United States | 2 | 58 |
| 16 | Kellyn Acosta | Los Angeles Football Club | United States | 11 | 57 |
| 17 | Brian Ching |  Houston Dynamo FC | United States | 10 | 56 |
| 18 | Jake Cox |  New York Red Bulls | United States | 7 | 56 |
| 19 | Eddie Johnson | Seattle Sounders FC | United States | 7 | 55 |
| 20 | Wil Trapp |  Columbus Crew | United States | 8 | 55 |
| 21 | Nate Phillips | Columbus Crew | United States | 8 | 54 |
| 22 | Jesus Ferreira | FC Dallas | United States | 7 | 52 |
| 23 | Wesley Gomez |  Philadelphia Union | United States | 9 | 52 |
| 24 | Chris Pontius | D.C. United | United States | 4 | 51 |
| 25 | Kellyn Acosta | Colorado Rapids | United States | 9 | 51 |
| 26 | Ricardo Clark | Houston Dynamo FC | United States | 3 | 50 |
| 27 | Jack Jewsbury |  Portland Timbers | United States | 8 | 50 |
| 28 | Ethan Jones |  San Diego FC | United States | 10 | 49 |
| 29 | Carson Rodriguez |  Orlando City SC | United States | 7 | 48 |
| 30 | Ben Olsen | D.C. United | United States | 10 | 46 |
| 31 | Brek Shea | FC Dallas | United States | 12 | 46 |
| 32 | Justin Anderson |  Inter Miami CF | United States | 8 | 46 |
| 33 | Caleb Cox | Seattle Sounders FC | United States | 6 | 46 |
| 34 | Jake Adams | Los Angeles Football Club | United States | 7 | 46 |
| 35 | Chance Gutierrez | Toronto FC | United States | 7 | 45 |
| 36 | Shane Cruz |  St. Louis City SC | United States | 10 | 44 |
| 37 | Dax McCarty | New York Red Bulls | United States | 14 | 43 |
| 38 | Kane Taylor |  Charlotte FC | United States | 7 | 43 |
| 39 | Brandon Campbell | San Diego FC | United States | 8 | 43 |
| 40 | Hunter Martin |  Atlanta United FC | United States | 6 | 43 |
| 41 | Chris Klein | LA Galaxy | United States | 6 | 42 |
| 42 | Jordan Gomez | Houston Dynamo FC | United States | 6 | 41 |
| 43 | Brayden King | Atlanta United FC | United States | 9 | 41 |
| 44 | Kenny Arena | LA Galaxy | United States | 9 | 40 |
| 45 | Grant Martinez | Houston Dynamo FC | United States | 9 | 40 |
| 46 | Parker Wright | St. Louis City SC | United States | 7 | 40 |
| 47 | Wesley Murphy | Houston Dynamo FC | United States | 7 | 39 |
| 48 | Caden Garcia | St. Louis City SC | United States | 7 | 36 |
| 49 | Jesse Marsch | D.C. United | United States | 5 | 36 |
| 50 | Wesley Torres | Orlando City SC | United States | 8 | 36 |