| 1 | Jaime Moreno |  D.C. United | Bolivia | 14 | 133 |
| 2 | Bradley Wright-Phillips |  New York Red Bulls | England | 8 | 108 |
| 3 | Robbie Keane |  LA Galaxy | Ireland | 6 | 104 |
| 4 | Carlos Ruiz | LA Galaxy | Guatemala | 8 | 91 |
| 5 | Josef Martinez |  Atlanta United FC | Venezuela | 5 | 90 |
| 6 | Karol Swiderski |  Charlotte FC | Poland | 8 | 88 |
| 7 | Diego Valeri |  Portland Timbers | Argentina | 10 | 86 |
| 8 | Teemu Pukki |  Minnesota United FC | Finland | 8 | 85 |
| 9 | Sebastian Giovinco |  Toronto FC | Italy | 5 | 83 |
| 10 | Jacob Shaffelburg |  Nashville SC | Canada | 8 | 83 |
| 11 | Dwayne De Rosario | D.C. United | Canada | 13 | 82 |
| 12 | Nery Castillo |  Chicago Fire FC | Mexico | 7 | 81 |
| 13 | David Villa |  New York City FC | Spain | 4 | 80 |
| 14 | Jack Harrison | New York City FC | England | 8 | 80 |
| 15 | Brenner |  FC Cincinnati | Brazil | 11 | 80 |
| 16 | Diego Rossi | Los Angeles Football Club | Uruguay | 10 | 76 |
| 17 | Joao Klauss |  St. Louis City SC | Brazil | 5 | 75 |
| 18 | Carlos Vela | Los Angeles Football Club | Mexico | 6 | 72 |
| 19 | Steve Zakuani |  Seattle Sounders FC | DR Congo | 10 | 71 |
| 20 | Alvaro Saborio |  Real Salt Lake | Costa Rica | 10 | 69 |
| 21 | Sven Becker |  Orlando City SC | Spain | 9 | 68 |
| 22 | Ercan Kara | Orlando City SC | Austria | 13 | 67 |
| 23 | Marcus Ingvartsen |  San Diego FC | Denmark | 3 | 63 |
| 24 | Samuel Diop | FC Cincinnati | Cameroon | 10 | 63 |
| 25 | Juan Pablo Angel | New York Red Bulls | Colombia | 4 | 62 |
| 26 | Chidi Ba | New York Red Bulls | Nigeria | 10 | 62 |
| 27 | Luciano Diaz | Nashville SC | Cuba | 9 | 61 |
| 28 | Daichi Hayashi |  Philadelphia Union | Japan | 8 | 61 |
| 29 | Ignacio Piatti | CF Montréal | Argentina | 6 | 60 |
| 30 | Fredy Montero | Seattle Sounders FC | Colombia | 7 | 60 |
| 31 | George Weber | D.C. United | Bosnia | 10 | 60 |
| 32 | Niklas Weber | Los Angeles Football Club | Poland | 8 | 59 |
| 33 | Thiago Suarez | St. Louis City SC | Cuba | 8 | 59 |
| 34 | Hugo King | Nashville SC | Portugal | 8 | 59 |
| 35 | Taty Castellanos | New York City FC | Argentina | 4 | 58 |
| 36 | Adolfo Bautista | Chicago Fire FC | Mexico | 13 | 58 |
| 37 | Eduard Atuesta | Los Angeles Football Club | Colombia | 11 | 58 |
| 38 | Jonathan Osorio | Toronto FC | Canada | 5 | 57 |
| 39 | Juninho | LA Galaxy | Brazil | 4 | 57 |
| 40 | Leandro Molina | New York City FC | Venezuela | 8 | 57 |
| 41 | Viktor Laurent | New York Red Bulls | Poland | 9 | 57 |
| 42 | Souleymane Ndiaye |  New England Revolution | Ghana | 10 | 57 |
| 43 | Julian Walker | Orlando City SC | Finland | 8 | 57 |
| 44 | Samuel Roberts | Charlotte FC | Bosnia | 9 | 57 |
| 45 | Nicolas Molina |  FC Dallas | Colombia | 10 | 56 |
| 46 | Miguel Rios |  Vancouver Whitecaps FC | Chile | 10 | 56 |
| 47 | Daniel Royer | New York Red Bulls | Austria | 10 | 55 |
| 48 | Maxi Moralez | New York City FC | Argentina | 5 | 55 |
| 49 | Joao Pedro |  Austin FC | Brazil | 13 | 55 |
| 50 | Gonzalo Vasquez |  Columbus Crew | Argentina | 8 | 55 |